Almitrine mesylate


Catalog No. Size PriceQuantity
M7616-2 2mg solid $90
M7616-10 10mg solid $270

Description

Almitrine mesylate (Almitrine bismesylate, Almitrine dimethanesulfonate, Almitrine dimesylate), a pharmacologically unique respiratory stimulant, acts as an agonist of peripheral chemoreceptors located on the carotid bodies. Almitrine mesylate inhibits the activity of Ca2+-dependent K+ channel by decreasing its open probability with IC50 of 0.22 μM.

Product information

CAS Number: 29608-49-9

Molecular Weight: 669.76

Formula: C28H37F2N7O6S2

Synonym:

Vectarion

Almitrin

Almitrina

Almitrinum

Related CAS Number:

27469-53-0 (Almitrine (free base))

Chemical Name: 6-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-N,N'-diprop-2-enyl-1,3,5-triazine-2,4-diamine

Smiles: CS(O)(=O)=O.CS(O)(=O)=O.C=CCNC1N=C(N=C(NCC=C)N=1)N1CCN(CC1)C(C1C=CC(F)=CC=1)C1C=CC(F)=CC=1

InChiKey: MRDBGMJEPGXQHJ-UHFFFAOYSA-N

InChi: InChI=1S/C26H29F2N7.2CH4O3S/c1-3-13-29-24-31-25(30-14-4-2)33-26(32-24)35-17-15-34(16-18-35)23(19-5-9-21(27)10-6-19)20-7-11-22(28)12-8-20;2*1-5(2,3)4/h3-12,23H,1-2,13-18H2,(H2,29,30,31,32,33);2*1H3,(H,2,3,4)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 100 mg/mL(149.3 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. J R López-López, et al. Mol Pharmacol. 1998 Feb;53(2):330-9.
  2. P D Smith, et al. Drug Intell Clin Pharm. 1987 May;21(5):417-21.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed