Description
U0126 is a potent and selective non-competitive inhibitor of MAP kinase. Inhibits MEK-1 and MEK-2 (IC50 values of 0.07 and 0.06 μM respectively).
Product information
CAS Number: 218601-62-8
Molecular Weight: 380.49
Formula: C18H16N6S2
Synonym:
U0126
U-0126
Related CAS Number:
1173097-76-1 (U0126-EtOH)
Chemical Name: (2Z, 3Z)-2, 3-bis(amino((2-aminophenyl)thio)methylene)succinonitrile
Smiles: NC1=CC=CC=C1S/C(/N)=C(\C#N)/C(/C#N)=C(\N)/SC1=CC=CC=C1N
InChiKey: DVEXZJFMOKTQEZ-JYFOCSDGSA-N
InChi: InChI=1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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