CAY10505


Catalog No. Size PriceQuantity
M7642-2 2mg solid $110
M7642-10 10mg solid $330

Description

CAY10505 is a phosphatidylinositol 3-kinase-γ inhibitor , was found to significantly improve acetylcholine-induced endothelium dependent relaxation, serum nitrate and (or) nitrite level, glutathione level, and the vascular endothelial lining in hypertensive rats. CAY10505 , may improve hypertension-associated vascular endothelial dysfunction. Inhibition of PI3Kγ might be a useful approach in the therapeutics of vascular endothelium dysfunction.

Product information

CAS Number: 1218777-13-9

Molecular Weight: 289.28

Formula: C14H8FNO3S

Synonym:

CAY 10505

Chemical Name: (E)-5-((5-(4-fluorophenyl)furan-2-yl)methylene)thiazolidine-2, 4-dione

Smiles: O=C1NC(=O)/C(=C\C2=CC=C(O2)C2C=CC(F)=CC=2)/S1

InChiKey: UFBTYTGRUBUUIL-KPKJPENVSA-N

InChi: InChI=1S/C14H8FNO3S/c15-9-3-1-8(2-4-9)11-6-5-10(19-11)7-12-13(17)16-14(18)20-12/h1-7H,(H,16,17,18)/b12-7+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 58 mg/mL(200.49 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Sun YY, et al. PLoS One, 2013, 8(7):e69019.

Products are for research use only. Not for human use.

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