Myricetin


Catalog No. Size PriceQuantity
M7683-2 2mg solid $95
M7683-10 10mg solid $285

Description

Myricetin is a COMT inhibitor found in fruits and vegetables. It exhibits a wide variety of biological activities, including decreasing cholesterol, triglyceride, and lipid levels, inhibiting amyloid-B-induced neurodegeneration, activating Wnt/B-catenin signaling to increase osteoclast differentiation, and inducing cell cycle arrest in oral squamous cell carcinoma cells.

Product information

CAS Number: 529-44-2

Molecular Weight: 318.24

Formula: C15H10O8

Synonym:

Cannabiscetin

HSDB 7682

HSDB7682

HSDB-7682

Chemical Name: 3, 5, 7-trihydroxy-2-(3, 4, 5-trihydroxyphenyl)-4H-chromen-4-one

Smiles: OC1C=C(C=C(O)C=1O)C1OC2C=C(O)C=C(O)C=2C(=O)C=1O

InChiKey: IKMDFBPHZNJCSN-UHFFFAOYSA-N

InChi: InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 63 mg/mL(197.96 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Myricetin(Cannabiscetin) is a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which has antioxidant and anti tumor properties. Myricetin has antioxidant properties. In vitro research suggests that myricetin in high concentrations can modify LDL cholesterol such that uptake by white blood cells is increased. Studies shows that high myricetin consumption reduces the risk of prostate cancer and pancreatic cancer.

References:

  1. Phillips PA, et al. Cancer Lett, 2011, 308(2), 181-188.
  2. Nothlings U, et al. Am J Epidemiol, 2007, 166(8), 924-931.
  3. Knekt P, et al. Am J Clin Nutr, 2002, 76(3), 560-568.

Products are for research use only. Not for human use.

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