Salicin

Salicin is a natural COX inhibitor.

Product information

CAS Number: 138-52-3

Molecular Weight: 286.28

Formula: C13H18O7

Synonym:

NSC 5751

NSC-5751

NSC5751

Chemical Name: (2R, 3S, 4S, 5R, 6S)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3, 4, 5-triol

Smiles: O[C@@H]1[C@@H](O)[C@@H](O[C@H](CO)[C@H]1O)OC1=CC=CC=C1CO

InChiKey: NGFMICBWJRZIBI-UJPOAAIJSA-N

InChi: InChI=1S/C13H18O7/c14-5-7-3-1-2-4-8(7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 57 mg/mL(199.1 mM). Water: 24 mg/mL(83.83 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. Salicin is a prodrug which is gradually transported to the lower part of the intestine, hydrolyzed to saligenin by intestinal bacteria, and converted to salicylic acid after absorption. It thus produces an antipyretic action without causing gastric injury.

References:

1. Jun Yan He, et al. Columbia Research SCholars Journal, 2016.
2. Akao T, et al. Planta Med, 2002, 68(8), 714-718.
3. Maclagan T, et al. Br Med J, 1876, 1(803), 627.

Products are for research use only. Not for human use.