Catalog No. Size PriceQuantity
M7698-2 2mg solid $80
M7698-10 10mg solid $240


Sclareol is a diterpene compound with a labdane skeleton, is mainly used as a raw material in the fragrance industry. It shows potent cytotoxic and cytostatic effect in human leukemic cell lines.

Product information

CAS Number: 515-03-7

Molecular Weight: 308.50

Formula: C20H36O2

Chemical Name: (1R, 2R, 4aS, 8aS)-1-((R)-3-hydroxy-3-methylpent-4-en-1-yl)-2, 5, 5, 8a-tetramethyldecahydronaphthalen-2-ol

Smiles: CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@](C)(O)[C@@H]2CC[C@@](C)(O)C=C


InChi: InChI=1S/C20H36O2/c1-7-18(4,21)13-9-16-19(5)12-8-11-17(2,3)15(19)10-14-20(16,6)22/h7,15-16,21-22H,1,8-14H2,2-6H3/t15-,16+,18-,19-,20+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 61 mg/mLwarmed(197.73 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts antitumor effects in various cell lines. Sclareol is able to inhibit DNA synthesis induce arrest at the G(0/1) phase of the cycle apoptosis independent of p53 in human breast cancer cell lines. Intra-tumoral injection of Sclareol reduces tumor growth in vivo against breast cancer. Sclareol also exhibits anti-inflammatory activity in LPS-stimulated macrophages by decreasing inflammatory cytokines expression and increasing antioxidant enzyme activity.

In Vivo:

LD50: Rats >5g/kg (i.g.)


  1. Huang GJ, et al. J Nat Prod, 2012, 75(1), 54-59.
  2. Noori S, et al. Cell Immunol, 2010, 263(2), 148-153.
  3. Dimas K, et al. Biomed Pharmacother, 2006, 60(3), 127-133.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed