Vanillylacetone


Catalog No. Size PriceQuantity
M7706-2 2mg solid $80
M7706-10 10mg solid $240

Description

Vanillylacetone is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties. Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.

Product information

CAS Number: 122-48-5

Molecular Weight: 194.23

Formula: C11H14O3

Synonym:

Zingerone

AI3-31837

Gingerone

Chemical Name: 4-(4-hydroxy-3-methoxyphenyl)butan-2-one

Smiles: CC(=O)CCC1=CC(OC)=C(O)C=C1

InChiKey: OJYLAHXKWMRDGS-UHFFFAOYSA-N

InChi: InChI=1S/C11H14O3/c1-8(12)3-4-9-5-6-10(13)11(7-9)14-2/h5-7,13H,3-4H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 38 mg/mLwarmed(195.64 mM). Water: 10 mg/mLwarmed(51.48 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas. Fresh ginger does not contain vanillylacetone; cooking the ginger transforms gingerol, which is present, into vanillylacetone through a retro-aldol reaction. Vanillylacetone is likely the active constituent responsible for the antidiarrheal efficacy of ginger.

References:

  1. Bilal Ahmad, et al. Saudi Pharm J . 2018 Dec;26(8):1137-1145.
  2. Chen JC, et al. J Agric Food Chem, 2007, 55(21), 8390-8397.

Products are for research use only. Not for human use.

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