Yohimbine Hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine.
CAS Number: 65-19-0
Molecular Weight: 390.90
Yohimbic acid methyl ester
Related CAS Number:
Chemical Name: methyl (1S, 15R, 18S, 19R, 20S)-18-hydroxy-3, 13-diazapentacyclo[126.96.36.199, .0, .0, ]henicosa-2(10), 4(9), 5, 7-tetraene-19-carboxylate hydrochloride
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
Yohimbine(Antagonil) has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac. Yohimbine is a pre-synaptic alpha 2-adrenergic blocking agent. Yohimbine may exert its beneficial effect on erectile ability through blockade of central alpha 2-adrenergic receptors producing an increase in sympathetic drive secondary to an increase in norepinephrine release and in firing rate of cells in the brain noradrenergic nuclei.
LD50: Mice 55mg/kg (i.p.)
- Wink M, et al. J Chem Ecol, 1998, 24(11), 1881-1937
- Banihashemi L, et al. J Neurosci, 2006, 26(44), 11442-11453.
- Ernst E, et al. J Urol, 1998, 159(2), 433-436.
Products are for research use only. Not for human use.
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