Hordenine inhibits the activity of PDK3, inhibits quorum sensing, and acts as an antibiofilm agent against bacteria.
CAS Number: 539-15-1
Molecular Weight: 165.23
Chemical Name: p-(2-Dimethylaminoethyl)phenol
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 33 mg/mL(199.72 mM). Water: Insoluble.
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
Hordenine (N, N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. It inhibits the uptake of norepinephrine in mammals, working as a stimulant. It is produced in nature by several varieties of plants in the family Cactaceae and by some in Acacia. Recent study shows that hordenine may be an effective inhibitor of hyperpigmentation. it inhibits melanogenesis by suppressing cAMP production, which is involved in the expression of melanogenesis-related proteins.
LD50: Mice 113.5mg/kg
- Kim SC, et al. Food Chem, 2013, 141(1), 174-181.
- Barwell CJ, et al. J Pharm Pharmacol, 1989, 41(6), 421-423.
Products are for research use only. Not for human use.
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