KW-2478


Catalog No. Size PriceQuantity
M7917-2 2mg solid $195
M7917-10 10mg solid $665

Description

KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be fully elucidated, Hsp90 antagonist KW-2478 appears to inhibit Hsp90, resulting in impaired signal transduction, inhibition of cell proliferation, and the induction of apoptosis in tumor cells.

Product information

CAS Number: 819812-04-9

Molecular Weight: 574.66

Formula: C30H42N2O9

Related CAS Number:

819812-18-5 (KW-2478 hydrochloride)

Chemical Name: 2-(2-ethyl-3, 5-dihydroxy-6-(3-methoxy-4-(2-morpholinoethoxy)benzoyl)phenyl)-N, N-bis(2-methoxyethyl)acetamide

Smiles: CCC1=C(CC(=O)N(CCOC)CCOC)C(C(=O)C2=CC(OC)=C(C=C2)OCCN2CCOCC2)=C(O)C=C1O

InChiKey: VFUXSYAXEKYYMB-UHFFFAOYSA-N

InChi: InChI=1S/C30H42N2O9/c1-5-22-23(19-28(35)32(11-13-37-2)12-14-38-3)29(25(34)20-24(22)33)30(36)21-6-7-26(27(18-21)39-4)41-17-10-31-8-15-40-16-9-31/h6-7,18,20,33-34H,5,8-17,19H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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