MK-0752


Catalog No. Size PriceQuantity
M7921-2 2mg solid $260
M7921-10 10mg solid $990

Description

MK0752 is a synthetic small molecule with potential antineoplastic activity. MK0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated. The Notch signaling pathway plays an important role in cell-fate determination, cell survival, and cell proliferation.

Product information

CAS Number: 471905-41-6

Molecular Weight: 442.90

Formula: C21H21ClF2O4S

Synonym:

cis34(3chlorophenyl)sulfonyl4(25difluorophenyl)cyclohexyl propanoicacid

Chemical Name: 3-((1r, 4s)-4-((4-chlorophenyl)sulfonyl)-4-(2, 5-difluorophenyl)cyclohexyl)propanoic acid.

Smiles: OC(=O)CC[C@@H]1CC[C@@](CC1)(C1=CC(F)=CC=C1F)S(=O)(=O)C1C=CC(Cl)=CC=1

InChiKey: XCGJIFAKUZNNOR-HNSKJHPRSA-N

InChi: InChI=1S/C21H21ClF2O4S/c22-15-2-5-17(6-3-15)29(27,28)21(18-13-16(23)4-7-19(18)24)11-9-14(10-12-21)1-8-20(25)26/h2-7,13-14H,1,8-12H2,(H,25,26)/t14-,21-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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