Description
MK0752 is a synthetic small molecule with potential antineoplastic activity. MK0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated. The Notch signaling pathway plays an important role in cell-fate determination, cell survival, and cell proliferation.
Product information
CAS Number: 471905-41-6
Molecular Weight: 442.90
Formula: C21H21ClF2O4S
Synonym:
cis34(3chlorophenyl)sulfonyl4(25difluorophenyl)cyclohexyl propanoicacid
Chemical Name: 3-((1r, 4s)-4-((4-chlorophenyl)sulfonyl)-4-(2, 5-difluorophenyl)cyclohexyl)propanoic acid.
Smiles: OC(=O)CC[C@@H]1CC[C@@](CC1)(C1=CC(F)=CC=C1F)S(=O)(=O)C1C=CC(Cl)=CC=1
InChiKey: XCGJIFAKUZNNOR-HNSKJHPRSA-N
InChi: InChI=1S/C21H21ClF2O4S/c22-15-2-5-17(6-3-15)29(27,28)21(18-13-16(23)4-7-19(18)24)11-9-14(10-12-21)1-8-20(25)26/h2-7,13-14H,1,8-12H2,(H,25,26)/t14-,21-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.