Nimbolide is a natural inhibitor of pancreatic cancer growth and metastasis through ROS-mediated apoptosis. It inhibits epithelial-to-mesenchymal transition.
CAS Number: 25990-37-8
Molecular Weight: 466.52
Chemical Name: 8(R)-(3-Furanyl)-2aR, 5aR, 6S, 6aR, 8R, 9, 9aR, 10aS, 10bR, 10cR-decahydro-2a, 5a, 6a, 7-tetramethyl-2, 5-dioxo-2H, 5H-cyclopenta[d']naphtho[1, 8-bc:2, 3-b']difuran-6-acetic acid, methyl ester
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
- Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. Toxicol In Vitro. 2014 Aug;28(5):1026-35.
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