Theophylline


Catalog No. Size PriceQuantity
M8068-2 Solid 2 mg $80
M8068-10 Solid 10 mg $240

Description

Theophylline is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.

Product information

CAS Number: 58-55-9

Molecular Weight: 179.17

Formula: C9H9NO3

Synonym:

1,3-dimethylxanthine

Accurbron

Aerobin

Aerolate

Afonilum

Retard

Anhydrous

Aquaphyllin

Armophylline

Related CAS Number:

5967-84-0 (hydrate)

Chemical Name: 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

Smiles: CN1CC(O)C2=CC(=O)C(=O)C=C12

InChiKey: RPHLQSHHTJORHI-UHFFFAOYSA-N

InChi: InChI=1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 11.11 mg/mL (61.67 mM; Need ultrasonic) H2O : 5 mg/mL (27.75 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Deree J, et al. Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition. Clinics (Sao Paulo). 2008 Jun;63(3):321-8.
  2. Marques LJ, et al. Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages. Am J Respir Crit Care Med. 1999 Feb;159(2):508-11.
  3. Daly JW, et al. Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63.

Products are for research use only. Not for human use.

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