Catalog No. Size PriceQuantity
M8125-2 Solid 2 mg $165
M8125-10 Solid 10 mg $515


H-1152 is a selective inhibitor of ROCK. H-1152 effects on intraocular pressure and trabecular meshwork morphology of rat eyes. H-1152 is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.

Product information

CAS Number: 451462-58-1

Molecular Weight: 319.42

Formula: C16H21N3O2S


H 1152


Chemical Name: 4-methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline

Smiles: CC1=CN=CC2=CC=CC(=C12)S(=O)(=O)N1CCCNC[C@@H]1C


InChi: InChI=1S/C16H21N3O2S/c1-12-9-18-11-14-5-3-6-15(16(12)14)22(20,21)19-8-4-7-17-10-13(19)2/h3,5-6,9,11,13,17H,4,7-8,10H2,1-2H3/t13-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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