Bay-K-8644 (R)

(R)-(+)-BAY-K-8644 is an L-type channel blocker that has negative inotropic and vasodilatory effects. Intracerebroventricular administration of this enantiomer has no effect on motor function in mice, whereas (S)-(−)-BAY-K-8644 impairs rotarod and motor activity, an effect that is blocked by (R)-(+)-BAY-K-8644.

Product information

CAS Number: 98791-67-4

Molecular Weight: 356.30

Formula: C16H15F3N2O4

Synonym:

(R)-(+)-Bay-K-8644

R-4407

NI-105

(+)-BAY-K-8644

Chemical Name: methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate

Smiles: COC(=O)C1[C@H](C(=C(C)NC=1C)[N+]([O-])=O)C1=CC=CC=C1C(F)(F)F

InChiKey: ZFLWDHHVRRZMEI-CYBMUJFWSA-N

InChi: InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.