MDL 105519

Catalog No. Size PriceQuantity
M8160-2 Solid 2 mg $165
M8160-10 Solid 10 mg $515


MDL-105519 is a high affinity NMDA glutamate receptor antagonist at the glycine site. MDL 105,519 prevented harmaline-stimulated increases in cerebellar cyclic GMP content, providing biochemical evidence of NMDA receptor antagonism in vivo. This antagonism was associated with anticonvulsant activity in genetically based, chemically induced, and electrically mediated seizure models.

Product information

CAS Number: 161230-88-2

Molecular Weight: 376.19

Formula: C18H11Cl2NO4



Chemical Name: 3-[(1E)-2-carboxy-2-phenyleth-1-en-1-yl]-4,6-dichloro-1H-indole-2-carboxylic acid

Smiles: OC(=O)/C(=C/C1C2C(=CC(Cl)=CC=2Cl)NC=1C(O)=O)/C1C=CC=CC=1


InChi: InChI=1S/C18H11Cl2NO4/c19-10-6-13(20)15-12(16(18(24)25)21-14(15)7-10)8-11(17(22)23)9-4-2-1-3-5-9/h1-8,21H,(H,22,23)(H,24,25)/b11-8+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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