Description
GANT58 is a cell-permeable tetrapyridinylthiophene compound that acts as downstream Hedgehog (Hh) pathway blocker and targets Gli-mediated gene transactivation (IC50 ~ 5 µM in SAG-stimulated Shh-L2 cells).
Product information
CAS Number: 64048-12-0
Molecular Weight: 392.48
Formula: C24H16N4S
Synonym:
NSC 75503
GANT58
GANT-58
NSC-75503
Chemical Name: 4-[3,4,5-tris(pyridin-4-yl)thiophen-2-yl]pyridine
Smiles: C1=CN=CC=C1C1SC(=C(C=1C1C=CN=CC=1)C1C=CN=CC=1)C1C=CN=CC=1
InChiKey: USWLOKMMUTWFMD-UHFFFAOYSA-N
InChi: InChI=1S/C24H16N4S/c1-9-25-10-2-17(1)21-22(18-3-11-26-12-4-18)24(20-7-15-28-16-8-20)29-23(21)19-5-13-27-14-6-19/h1-16H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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