K-115 free base


Catalog No. Size PriceQuantity
M8198-2 Solid 2 mg $120
M8198-10 Solid 10 mg $360

Description

Ripasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.

Product information

CAS Number: 223645-67-8

Molecular Weight: 323.39

Formula: C15H18FN3O2S

Synonym:

Ripasudil free base

K 115 free base

K115 free base

Chemical Name: 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline

Smiles: C[C@H]1CNCCCN1S(=O)(=O)C1=CC=CC2=CN=CC(F)=C21

InChiKey: QSKQVZWVLOIIEV-NSHDSACASA-N

InChi: InChI=1S/C15H18FN3O2S/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14/h2,4-5,9-11,17H,3,6-8H2,1H3/t11-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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