Losartan D4


Catalog No. Size PriceQuantity
M8286-2 Solid 2 mg $590
M8286-10 Solid 10 mg $2,360

Description

Losartan D4 (DuP-753 D4) is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

Product information

CAS Number: 1030937-27-9

Molecular Weight: 426.94

Formula: C22H23ClN6O

Synonym:

DuP-753 D4

Cozaar D4

Chemical Name: (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-²H₄)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol

Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CO)=C(Cl)N=C2CCCC)C=1[2H]

InChiKey: PSIFNNKUMBGKDQ-IRYCTXJYSA-N

InChi: InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)/i9D,10D,11D,12D

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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