Fluvastatin D6 Sodium


Catalog No. Size PriceQuantity
M8292-2 Contact sales@xcessbio.com for quotation $100
M8292-10 Contact sales@xcessbio.com for quotation $100

Description

Fluvastatin D6 sodium (XU 62-320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.

Product information

CAS Number: 2070009-35-5

Molecular Weight: 439.48

Formula: C24H25FNNaO4

Chemical Name: sodium (3R, 5S, 6E)-7-[3-(4-fluorophenyl)-1-[(1, 1, 1, 3, 3, 3-H)propan-2-yl]-1H-indol-2-yl]-3, 5-dihydroxyhept-6-enoate

Smiles: [Na+].[2H]C([2H])([2H])C(N1C2=CC=CC=C2C(=C1/C=C/[C@@H](O)C[C@@H](O)CC([O-])=O)C1C=CC(F)=CC=1)C([2H])([2H])[2H]

InChiKey: ZGGHKIMDNBDHJB-VOEOVFABSA-M

InChi: InChI=1S/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/q;+1/p-1/b12-11+;/t18-,19-;/m1./s1/i1D3,2D3;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Yin N, Zhang H, Ye R, Dong M, Lin J, Zhou H, Huang Y, Chen L, Jiang X, Nagaoka K, Zhang C, Jin W. Fluvastatin Sodium Ameliorates Obesity through Brown Fat Activation. Int J Mol Sci. 2019 Apr 1;20(7):1622.
  2. Singh S, Sharma N, Kaur G. Central composite designed solid dispersion for dissolution enhancement of fluvastatin sodium by kneading technique. Ther Deliv. 2020 May;11(5):313-328.

Products are for research use only. Not for human use.

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