Rhosin


Catalog No. Size PriceQuantity
M8351-2 Solid 2 mg $120
M8351-10 Solid 10 mg $360

Description

Rhosin is an inhibitor of RhoA and RhoC interaction with GEFs. It acts by preventing RhoA activation and downstream MLC phosphorylation, filamentous actin formation and focal adhesion assembly without perturbing endogenous Cdc42 or Rac signalling.

Product information

CAS Number: 1173671-63-0

Molecular Weight: 358.40

Formula: C20H18N6O

Chemical Name: (2R)-2-amino-3-(1H-indol-3-yl)-N'-[(1E)-(quinoxalin-6-yl)methylidene]propanehydrazide

Smiles: N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N/N=C/C1=CC2=NC=CN=C2C=C1

InChiKey: FGYHLIHEFHCMPP-FVWOBLMASA-N

InChi: InChI=1S/C20H18N6O/c21-16(10-14-12-24-17-4-2-1-3-15(14)17)20(27)26-25-11-13-5-6-18-19(9-13)23-8-7-22-18/h1-9,11-12,16,24H,10,21H2,(H,26,27)/b25-11+/t16-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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