Pyridostatin Hydrochloride


Catalog No. Size PriceQuantity
M8363-2 Solid 2 mg $100
M8363-10 Solid 10 mg $300

Description

Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.

Product information

CAS Number: 1781882-65-2

Molecular Weight: 778.94

Formula: C31H37Cl5N8O5

Chemical Name: 4-(2-aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide pentahydrochloride

Smiles: Cl.Cl.Cl.Cl.Cl.NCCOC1C=C(N=C(C=1)C(=O)NC1=CC(OCCN)=C2C=CC=CC2=N1)C(=O)NC1=CC(OCCN)=C2C=CC=CC2=N1

InChiKey: SRIZPFGTXSQRFM-UHFFFAOYSA-N

InChi: InChI=1S/C31H32N8O5.5ClH/c32-9-12-42-19-15-24(30(40)38-28-17-26(43-13-10-33)20-5-1-3-7-22(20)36-28)35-25(16-19)31(41)39-29-18-27(44-14-11-34)21-6-2-4-8-23(21)37-29;;;;;/h1-8,15-18H,9-14,32-34H2,(H,36,38,40)(H,37,39,41);5*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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