Tegaserod maleate


Catalog No. Size PriceQuantity
M8408-2 Solid 2 mg $85
M8408-10 Solid 10 mg $255

Description

Tegaserod, also known as SDZ-HTF-919; HTF 919 is a 5-HT4 agonist for the management of irritable bowel syndrome and constipation. Approved by the FDA in 2002, it was subsequently removed from the market in 2007 due to FDA concerns about possible adverse cardiovascular effects. Before then, it was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating, and constipation associated with irritable bowel syndrome. Its use was also approved to treat chronic idiopathic constipation.

Product information

CAS Number: 189188-57-6

Molecular Weight: 417.46

Formula: C20H27N5O5

Synonym:

Zelnorm

SDZ-HTF-919

HTF-919

Zelmac

Chemical Name: (2Z)-but-2-enedioic acid; N'-{[(5-methoxy-1H-indol-3-yl)methylidene]amino}-N-pentylguanidine

Smiles: CCCCCNC(=N)NN=CC1=CNC2=CC=C(C=C12)OC.OC(=O)/C=C\C(O)=O

InChiKey: CPDDZSSEAVLMRY-FEQFWAPWSA-N

InChi: InChI=1S/C16H23N5O.C4H4O4/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15;5-3(6)1-2-4(7)8/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21);1-2H,(H,5,6)(H,7,8)/b20-11+;2-1-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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