UPF-648 Sodium Salt

Catalog No. Size PriceQuantity
M8472-2 Solid 2 mg $210
M8472-10 Solid 10 mg $745


UPF-648 is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ± 10% KMO inhibition); ineffective at blocking KAT activity. IC50 value: 1 uM(81 ± 10 % inhibition) Target: KMO inhibitor in vitro: BFF 122 inhibited KAT activity almost completely at both 1 and 0.1 mM. The effect was still remarkable at 0.01 mM (70 ± 1 % inhibition).

Product information

CAS Number: 1465017-87-1

Molecular Weight: 281.07

Formula: C11H7Cl2NaO3

Chemical Name: sodium (1S, 2S)-2-(3, 4-dichlorobenzoyl)cyclopropane-1-carboxylate

Smiles: [Na+].[O-]C(=O)[C@H]1C[C@@H]1C(=O)C1C=CC(Cl)=C(Cl)C=1


InChi: InChI=1S/C11H8Cl2O3.Na/c12-8-2-1-5(3-9(8)13)10(14)6-4-7(6)11(15)16;/h1-3,6-7H,4H2,(H,15,16);/q;+1/p-1/t6-,7-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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