DZ2002

DZ-2002 is a potent reversible inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH). DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models. DZ2002 prevents the development of experimental dermal fibrosis by reversing the profibrotic phenotype of various cell types and would be a potential drug for the treatment of systemic sclerosis.

Product information

CAS Number: 33231-14-0

Molecular Weight: 251.24

Formula: C10H13N5O3

Synonym:

DZ-2002

Chemical Name: methyl 4-(6-amino-9H-purin-9-yl)-2-hydroxybutanoate

Smiles: COC(=O)C(O)CCN1C=NC2=C(N)N=CN=C12

InChiKey: HNKGMGPCSSJYOT-UHFFFAOYSA-N

InChi: InChI=1S/C10H13N5O3/c1-18-10(17)6(16)2-3-15-5-14-7-8(11)12-4-13-9(7)15/h4-6,16H,2-3H2,1H3,(H2,11,12,13)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.