Carboplatin


Catalog No. Size PriceQuantity
M8514-2 Solid 2 mg $75
M8514-10 Solid 10 mg $225

Description

Carboplatin is a second-generation platinum compound with a broad spectrum of antineoplastic properties. Carboplatin contains a platinum atom complexed with two ammonia groups and a cyclobutane-dicarboxyl residue. This agent is activated intracellularly to form reactive platinum complexes that bind to nucleophilic groups such as GC-rich sites in DNA, thereby inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These carboplatin-induced DNA and protein effects result in apoptosis and cell growth inhibition.

Product information

CAS Number: 41575-94-4

Molecular Weight: 371.25

Formula: C6H12N2O4Pt

Synonym:

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum

Chemical Name: platinum(2+) cyclobutane-1,1-dicarboxylic acid diazanide

Smiles: N.N.O=C1O[Pt]OC(=O)C21CCC2

InChiKey: OLESAACUTLOWQZ-UHFFFAOYSA-L

InChi: InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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