Adoprazine


Catalog No. Size PriceQuantity
M8536-2 Solid 2 mg $120
M8536-10 Solid 10 mg $360

Description

Adoprazine, also known as SLV313, is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug. SLV313 possessed high affinity at human recombinant D(2), D(3), D(4), 5-HT(2B), and 5-HT(1A) receptors, moderate affinity at 5-HT(7) and weak affinity at 5-HT(2A) receptors, with little-no affinity at 5-HT(4), 5-HT(6), alpha(1), and alpha(2) (rat), H(1) (guinea pig), M(1), M(4), 5-HT(3) receptors, and the 5-HT transporter. SLV313 had full agonist activity at cloned h5-HT(1A) receptors (pEC(50)=9.0) and full antagonist activity at hD(2) (pA(2)=9.3) and hD(3) (pA(2)=8.9) receptors.

Product information

CAS Number: 222551-17-9

Molecular Weight: 405.46

Formula: C24H24FN3O2

Synonym:

SLV 313

SLV313

SLV-313

Chemical Name: 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-{[5-(4-fluorophenyl)pyridin-3-yl]methyl}piperazine

Smiles: FC1C=CC(=CC=1)C1C=C(CN2CCN(CC2)C2=CC=CC3OCCOC=32)C=NC=1

InChiKey: IUVSEUFHPNITEQ-UHFFFAOYSA-N

InChi: InChI=1S/C24H24FN3O2/c25-21-6-4-19(5-7-21)20-14-18(15-26-16-20)17-27-8-10-28(11-9-27)22-2-1-3-23-24(22)30-13-12-29-23/h1-7,14-16H,8-13,17H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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