IRAK inhibitor 4 (trans)

IRAK inhibitor 4 (trans) is the trans form of IRAK inhibitor 4. IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor.

Product information

CAS Number: 2070014-89-8

Molecular Weight: 620.66

Formula: C33H35F3N6O3

Chemical Name: 1H-Benzimidazole-5-carboxamide, 1-(trans-4-hydroxycyclohexyl)-N-(3-methylbutyl)-2-[[5-[2-(trifluoromethoxy)phenyl]-1H-indazol-3-yl]amino]-

Smiles: CC(C)CCNC(=O)C1=CC=C2C(=C1)N=C(NC1=NNC3=CC=C(C=C13)C1=CC=CC=C1OC(F)(F)F)N2[C@@H]1CC[C@@H](O)CC1

InChiKey: QZMAOGLWCNTFCG-YHBQERECSA-N

InChi: InChI=1S/C33H35F3N6O3/c1-19(2)15-16-37-31(44)21-8-14-28-27(18-21)38-32(42(28)22-9-11-23(43)12-10-22)39-30-25-17-20(7-13-26(25)40-41-30)24-5-3-4-6-29(24)45-33(34,35)36/h3-8,13-14,17-19,22-23,43H,9-12,15-16H2,1-2H3,(H,37,44)(H2,38,39,40,41)/t22-,23-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 38 mg/mL (61.23 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Indazole derivatives as modulators of interleukin-1 receptor-associated kinase. Patent WO 2008030584 A2.

Products are for research use only. Not for human use.