Catalog No. Size PriceQuantity
M8545-2 Solid 2 mg $105
M8545-10 Solid 10 mg $315


CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM. It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM). The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.

Product information

CAS Number: 1421693-22-2

Molecular Weight: 394.45

Formula: C15H15FN6O2S2

Chemical Name: 3-({5-fluoro-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl}amino)benzene-1-sulfonamide

Smiles: CC1N=C(NC)SC=1C1=NC(NC2=CC(=CC=C2)S(N)(=O)=O)=NC=C1F


InChi: InChI=1S/C15H15FN6O2S2/c1-8-13(25-15(18-2)20-8)12-11(16)7-19-14(22-12)21-9-4-3-5-10(6-9)26(17,23)24/h3-7H,1-2H3,(H,18,20)(H2,17,23,24)(H,19,21,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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