Y15


Catalog No. Size PriceQuantity
M8546-2 Solid 2 mg $80
M8546-10 Solid 10 mg $240

Description

Y15 hydrochloride, also known as FAK Inhibitor 14, is a direct FAK autophosphorylation inhibitor, blocking phosphorylation of Y397 with an IC50 value of about 1 μM. Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeutics. Y15 was shown to decrease cancer growth in vitro and in vivo.

Product information

CAS Number: 4506-66-5

Molecular Weight: 174.63

Formula: C6H11ClN4

Synonym:

FAK inhibitor Y15

Y-15

FAK Inhibitor 14

Chemical Name: benzene-1,2,4,5-tetramine hydrochloride

Smiles: Cl.NC1C=C(N)C(N)=CC=1N

InChiKey: NZLYXIUDQUBQGU-UHFFFAOYSA-N

InChi: InChI=1S/C6H10N4.ClH/c7-3-1-4(8)6(10)2-5(3)9;/h1-2H,7-10H2;1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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