Catalog No. Size PriceQuantity
M8562-2 Solid 2 mg $130
M8562-10 Solid 10 mg $390


MPS1-IN-3 is a selective and potent MPS1 inhibitor with phenotypic consequences similar to those reported for published MPS1 inhibitors such as MPS1-IN-1, MPS1-IN-2, and AZD3146. MPS1-IN-3 sensitizes glioblastoma cells to vincristine both in vitro and in murine tumor models. MPS1 may be a promising therapeutic target for high-grade glioma therapy and that MPS1 inhibition by MPS1-IN-3 efficiently sensitizes glioblastoma cells to antimitotic agents.

Product information

CAS Number: 1609584-72-6

Molecular Weight: 537.63

Formula: C26H31N7O4S



Chemical Name: 1-{3-methoxy-4-[(6-{[2-(propane-2-sulfonyl)phenyl]amino}-7H-purin-2-yl)amino]phenyl}piperidin-4-ol

Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(NC2=CC=C(C=C2OC)N2CCC(O)CC2)=NC2N=CNC1=2


InChi: InChI=1S/C26H31N7O4S/c1-16(2)38(35,36)22-7-5-4-6-20(22)29-25-23-24(28-15-27-23)31-26(32-25)30-19-9-8-17(14-21(19)37-3)33-12-10-18(34)11-13-33/h4-9,14-16,18,34H,10-13H2,1-3H3,(H3,27,28,29,30,31,32)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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