BMS-345541 hydrochloride

Catalog No. Size PriceQuantity
M8565-2 Solid 2 mg $95
M8565-10 Solid 10 mg $285


BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). It attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis.

Product information

CAS Number: 547757-23-3

Molecular Weight: 291.78

Formula: C14H18ClN5


BMS345541 hydrochloride

BMS-345541 hydrochloride

BMS 345541 hydrochloride

Chemical Name: N1-{1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl}ethane-1,2-diamine hydrochloride

Smiles: Cl.CC1=CC2=C(C=C1)N=C(NCCN)C1=NC=C(C)N21


InChi: InChI=1S/C14H17N5.ClH/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15;/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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