MMAD Hydrochloride

Catalog No. Size PriceQuantity
M8609-2 Contact for quotation $100
M8609-10 Contact for quotation $100


MMAD, also known as Monomethyl auristatin D, is a highly potent tubulin inhibitor. MMAD is one of the auristatins, which are used as antibody drug conjugates (ADCs).

Product information

CAS Number: 173441-26-4

Molecular Weight: 807.53

Formula: C41H67ClN6O6S


Demethyldolastatin 10 hydrochloride

Monomethylauristatin D hydrochloride

Monomethyl Dolastatin 10 hydrochloride

Chemical Name: (2S)-N-[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-2-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]carbamoyl}ethyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethyl-2-[(2S)-3-methyl-2-(methylamino)butanamido]butanamide hydrochloride

Smiles: Cl.CN([C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1C=CC=CC=1)C1=NC=CS1)OC)[C@@H](C)CC)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C


InChi: InChI=1S/C41H66N6O6S.ClH/c1-12-27(6)36(46(9)41(51)35(26(4)5)45-39(50)34(42-8)25(2)3)32(52-10)24-33(48)47-21-16-19-31(47)37(53-11)28(7)38(49)44-30(40-43-20-22-54-40)23-29-17-14-13-15-18-29;/h13-15,17-18,20,22,25-28,30-32,34-37,42H,12,16,19,21,23-24H2,1-11H3,(H,44,49)(H,45,50);1H/t27-,28+,30-,31-,32+,34-,35-,36-,37+;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.

Products are for research use only. Not for human use.

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