Rostafuroxin


Catalog No. Size PriceQuantity
M8617-2 Solid 2 mg $100
M8617-10 Solid 10 mg $300

Description

Rostafuroxin, also known as PST-2238, is an ouabain antagonist. Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain. Rostafuroxin ameliorates endothelial dysfunction and oxidative stress in resistance arteries from deoxycorticosterone acetate-salt hypertensive rats: the role of Na+K+-ATPase/ cSRC pathway. Rostafuroxin corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension.

Product information

CAS Number: 156722-18-8

Molecular Weight: 374.51

Formula: C23H34O4

Synonym:

PST-2238

PST2238

PST 2238

Chemical Name: (1S,3aS,3bR,5aR,7S,9aS,9bS,11aS)-1-(furan-3-yl)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-1,3a,7-triol

Smiles: C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]1(O)CC[C@]2(O)C1C=COC=1

InChiKey: AEAPORIZZWBIEX-DTBDINHYSA-N

InChi: InChI=1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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