VU 0240551

Catalog No. Size PriceQuantity
M8631-2 Solid 2 mg $110
M8631-10 Solid 10 mg $330


VU0240551 is an inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2-overexpressing cells). VU0240551 exhibits selectivity over the Na-K-2Cl cotransporter, NKCCl. It also inhibits hERG and L-type Ca2+ channels.

Product information

CAS Number: 893990-34-6

Molecular Weight: 342.44

Formula: C16H14N4OS2




Chemical Name: N-(4-methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamide

Smiles: CC1=CSC(NC(=O)CSC2=CC=C(N=N2)C2=CC=CC=C2)=N1


InChi: InChI=1S/C16H14N4OS2/c1-11-9-23-16(17-11)18-14(21)10-22-15-8-7-13(19-20-15)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,17,18,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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