FR 180204


Catalog No. Size PriceQuantity
M8634-2 Solid 2 mg $100
M8634-10 Solid 10 mg $300

Description

FR180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.FR180204 showed activity to inhibit ERKs (IC50 values are 0.14 and 0.31 μ M for ERK2 and ERK1 respectively).

Product information

CAS Number: 865362-74-9

Molecular Weight: 327.34

Formula: C18H13N7

Synonym:

FR180204

FR-180204

Chemical Name: 5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-2H-pyrazolo[3,4-c]pyridazin-3-amine

Smiles: NC1NN=C2N=NC(=CC2=1)C1C(=NN2C=CC=CC2=1)C1C=CC=CC=1

InChiKey: XVECMUKVOMUNLE-UHFFFAOYSA-N

InChi: InChI=1S/C18H13N7/c19-17-12-10-13(20-22-18(12)23-21-17)15-14-8-4-5-9-25(14)24-16(15)11-6-2-1-3-7-11/h1-10H,(H3,19,21,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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