AGN 205327

Catalog No. Size PriceQuantity
M8635-2 Contact for quotation $100
M8635-10 Contact for quotation $100


AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR. IC50 value: 3766/734/32 nM for RARα/β/γ Target: RAR agonist.

Product information

CAS Number: 2070018-29-8

Molecular Weight: 390.47

Formula: C24H26N2O3




Chemical Name: 2-[(E)-N-Hydroxy-C-(5, 5, 8, 8-tetramethyl-6, 7-dihydronaphthalen-2-yl)carbonimidoyl]-1H-indole-5-carboxylic acid

Smiles: CC1(C)CCC(C)(C)C2=CC(=CC=C12)/C(=N\O)/C1=CC2=CC(=CC=C2N1)C(O)=O


InChi: InChI=1S/C24H26N2O3/c1-23(2)9-10-24(3,4)18-12-14(5-7-17(18)23)21(26-29)20-13-16-11-15(22(27)28)6-8-19(16)25-20/h5-8,11-13,25,29H,9-10H2,1-4H3,(H,27,28)/b26-21+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Brown G, Hughes P. Retinoid differentiation therapy for common types of acute myeloid leukemia. Leuk Res Treatment. 2012;2012:939021.

Products are for research use only. Not for human use.

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