AGN 205327


Catalog No. Size PriceQuantity
M8635-2 Contact sales@xcessbio.com for quotation $100
M8635-10 Contact sales@xcessbio.com for quotation $100

Description

AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR. IC50 value: 3766/734/32 nM for RARα/β/γ Target: RAR agonist.

Product information

CAS Number: 2070018-29-8

Molecular Weight: 390.47

Formula: C24H26N2O3

Synonym:

AGN205327

AGN-205327

Chemical Name: 2-[(E)-N-Hydroxy-C-(5, 5, 8, 8-tetramethyl-6, 7-dihydronaphthalen-2-yl)carbonimidoyl]-1H-indole-5-carboxylic acid

Smiles: CC1(C)CCC(C)(C)C2=CC(=CC=C12)/C(=N\O)/C1=CC2=CC(=CC=C2N1)C(O)=O

InChiKey: CTYNDNYSDMIEPV-YYADALCUSA-N

InChi: InChI=1S/C24H26N2O3/c1-23(2)9-10-24(3,4)18-12-14(5-7-17(18)23)21(26-29)20-13-16-11-15(22(27)28)6-8-19(16)25-20/h5-8,11-13,25,29H,9-10H2,1-4H3,(H,27,28)/b26-21+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Brown G, Hughes P. Retinoid differentiation therapy for common types of acute myeloid leukemia. Leuk Res Treatment. 2012;2012:939021.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed