AGN 205728

Catalog No. Size PriceQuantity
M8637-2 Contact for quotation $100
M8637-10 Contact for quotation $100


AGN 205728 is a potent and selective RARγ antagonist.

Product information

CAS Number: 859498-05-8

Molecular Weight: 437.53

Formula: C29H27NO3




Chemical Name: 4-[(1E,3E)-3-[8,8-dimethyl-5-(4-methylphenyl)-7,8-dihydronaphthalen-2-yl]-3-(hydroxyimino)prop-1-en-1-yl]benzoic acid

Smiles: CC1C=CC(=CC=1)C1=CCC(C)(C)C2=CC(=CC=C12)/C(/C=C/C1C=CC(=CC=1)C(O)=O)=N/O


InChi: InChI=1S/C29H27NO3/c1-19-4-9-21(10-5-19)24-16-17-29(2,3)26-18-23(13-14-25(24)26)27(30-33)15-8-20-6-11-22(12-7-20)28(31)32/h4-16,18,33H,17H2,1-3H3,(H,31,32)/b15-8+,30-27+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Tsang, Kwok Yin, et al. Preparation of disubstituted chalcone oximes having RARγ retinoid receptor antagonist activity. Appl. (2005), WO 2005066115 A2 20050721.

Products are for research use only. Not for human use.

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