Description
HLM006474 is a pan-E2F inhibitor. It inhibits DNA binding to E2F1, E2F2, and E2F4 in A375 melanoma cells when used at a concentration of 40 µM.
Product information
CAS Number: 353519-63-8
Molecular Weight: 399.48
Formula: C25H25N3O2
Synonym:
HLM 006474
HLM-006474
Chemical Name: 7-[(4-ethoxy-3-methylphenyl)[(pyridin-2-yl)amino]methyl]-2-methylquinolin-8-ol
Smiles: CCOC1=CC=C(C=C1C)C(NC1=CC=CC=N1)C1=CC=C2C=CC(C)=NC2=C1O
InChiKey: CYNZBLNMIJNBSF-UHFFFAOYSA-N
InChi: InChI=1S/C25H25N3O2/c1-4-30-21-13-11-19(15-16(21)2)23(28-22-7-5-6-14-26-22)20-12-10-18-9-8-17(3)27-24(18)25(20)29/h5-15,23,29H,4H2,1-3H3,(H,26,28)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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