Catalog No. Size PriceQuantity
M8649-2 Solid 2 mg $100
M8649-10 Solid 10 mg $300


ITX3 is a nontoxic selective cell active inhibitor of the Trio/RhoG​/Rac1 pathway. It acts by validating RhoGEFs as druggable targets.

Product information

CAS Number: 347323-96-0

Molecular Weight: 371.45

Formula: C22H17N3OS




Chemical Name: (4E)-4-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylidene]-5-thia-2,7-diazatricyclo[²,⁶]dodeca-1(12),6,8,10-tetraen-3-one

Smiles: CC1=C(/C=C2/SC3=NC4=CC=CC=C4N3C/2=O)C=C(C)N1C1C=CC=CC=1


InChi: InChI=1S/C22H17N3OS/c1-14-12-16(15(2)24(14)17-8-4-3-5-9-17)13-20-21(26)25-19-11-7-6-10-18(19)23-22(25)27-20/h3-13H,1-2H3/b20-13+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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