Description
Miglustat, also known as OGT 918 and NB-DNJ, is a drug developed by Actelion and is used primarily to treat Type I Gaucher disease (GD1). Miglustat inhibits glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids (it forms glucosylceramide and accumulates within the macrophages). Miglustat is used to treat adults with mild-to-moderate Type I Gaucher disease and it is the first treatment to be approved for patients with Niemann–Pick type C disease
Product information
CAS Number: 210110-90-0
Molecular Weight: 255.74
Formula: C10H22ClNO4
Synonym:
N-Butyldeoxynojirimycin, Hydrochloride
NB-DNJ hydrochloride
OGT918 hydrochloride
Zavesca hydrochloride
Chemical Name: (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride
Smiles: Cl.CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChiKey: QPAFAUYWVZMWPR-ZSOUGHPYSA-N
InChi: InChI=1S/C10H21NO4.ClH/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12;/h7-10,12-15H,2-6H2,1H3;1H/t7-,8+,9-,10-;/m1./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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