5(6)-TAMRA


Catalog No. Size PriceQuantity
M8812-2 Solid 2 mg $75
M8812-10 Solid 10 mg $225

Description

5(6)-TAMRA contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.

Product information

CAS Number: 98181-63-6

Molecular Weight: 430.45

Formula: C50H44N4O10

Synonym:

5(6)-Carboxytetramethylrhodamine

Chemical Name: 9-(4( or 5)-carboxy-2-carboxylatophenyl)-3, 6-bis(dimethylamino)-10-xanthen-10-ylium

Smiles: CN(C)C1=CC2=[O+]C3=CC(=CC=C3C(C3=CC=C(C=C3C([O-])=O)C(O)=O)=C2C=C1)N(C)C.CN(C)C1=CC2=[O+]C3=CC(=CC=C3C(C3=CC(=CC=C3C([O-])=O)C(O)=O)=C2C=C1)N(C)C

InChiKey: PYOXZPUMKLJOGA-UHFFFAOYSA-N

InChi: InChI=1S/2C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31;1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)17-8-5-14(24(28)29)11-20(17)25(30)31/h2*5-13H,1-4H3,(H-,28,29,30,31)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (290.39 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Fuchs SM, et al. Pathway for polyarginine entry into mammalian cells. Biochemistry. 2004 Mar 9;43(9):2438-44.
  2. Gerber D, et al. Insertion and organization within membranes of the delta-endotoxin pore-forming domain, helix 4-loop-helix 5, and inhibition of its activity by a mutant helix 4 peptide. J Biol Chem. 2000 Aug 4;275(31):23602-7.
  3. Vinayak R, et al. Automated, solid-phase coupling of rhodamine dye acids to 5' amino oligonucleotides. Nucleic Acids Symp Ser. 2000;(44):257-8.

Products are for research use only. Not for human use.

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