Description
Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression. It is a highly potent and selective ST (serotonin transporter/5-HT) uptake inhibitor. It acts by binding to ST (serotonin transporter/SERT) with high affinity. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex thereby blocking reuptake of serotonin by the pre-synaptic transporter. Paroxetine HCl has also displayed a high affinity for muscarinic acetylcholine receptors.
Product information
CAS Number: 78246-49-8
Molecular Weight: 365.83
Formula: C19H21ClFNO3
Synonym:
Paxil
Seroxat
BRL29060 hydrochloride
BRL29060A
Chemical Name: (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride
Smiles: Cl.FC1C=CC(=CC=1)[C@@H]1CCNC[C@H]1COC1=CC2OCOC=2C=C1
InChiKey: GELRVIPPMNMYGS-RVXRQPKJSA-N
InChi: InChI=1S/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14-,17-;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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