Doxapram (hydrochloride hydrate)


Catalog No. Size PriceQuantity
M8913-2 Solid 2 mg $80
M8913-10 Solid 10 mg $240

Description

Doxapram is a respiratory stimulant. Administered intravenously, Doxapram stimulates an increase in tidal volume and respiratory rate. Doxapram stimulates chemoreceptors in the carotid bodies of the carotid arteries, which in turn, stimulates the respiratory centre in the brain stem. Doxapram induced changes in the electrophysiological properties of pre-inspiratory and inspiratory neurones. Results suggest that respiratory activity enhancement was likely to be induced via effects on the potassium channels of pre-inspiratory and inspiratory neurones and indicate the central actions of doxapram.

Product information

CAS Number: 7081-53-0

Molecular Weight: 432.98

Formula: C24H33ClN2O3

Synonym:

Dopram hydrochloride hydrate

Stimulex hydrochloride hydrate

Respiram hydrochloride hydrate

Chemical Name: 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrate hydrochloride

Smiles: O.Cl.CCN1CC(CCN2CCOCC2)C(C1=O)(C1C=CC=CC=1)C1C=CC=CC=1

InChiKey: ZOMBFZRWMLIDPX-UHFFFAOYSA-N

InChi: InChI=1S/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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