Description
Tioxolone is an inhibitor of carbonic anhydrase I. It is selective for CAI over CAII, -III, -IV, -VA, -VB, -VI, -VII, -IX, -XII, and -XIV. Tioxolone is active against Gram-positive or -negative bacteria, including M. tuberculosis. It is also active against dermatophytes, yeasts, and molds.
Product information
CAS Number: 4991-65-5
Molecular Weight: 168.17
Formula: C7H4O3S
Synonym:
Acnosan
Tioxolon
Chemical Name: 6-hydroxy-2H-1,3-benzoxathiol-2-one
Smiles: OC1=CC2OC(=O)SC=2C=C1
InChiKey: SLYPOVJCSQHITR-UHFFFAOYSA-N
InChi: InChI=1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 100 mg/mL (594.64 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Maryam Hakimi Parizi, et al. Tioxolone niosomes exert antileishmanial effects on Leishmania tropica by promoting promastigote apoptosis and immunomodulation. Asian Pacific Journal of Tropical Medicine 2019; 12(8): 365-374.
Products are for research use only. Not for human use.
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