Description
Sodium Channel inhibitor1, one of 3-Oxoisoindoline-1-carboxamides, is a novel and selective voltage-gated sodium channel for pain treatment. IC50 Value: 0.16 uM ( Na v1.7, V hold-90mV); 0.41 uM (Na v1.7, V hold-90mV) Target: Na v1.7Sodium Channel inhibitor1 demonstrated concentration-dependent efficacy in preclinical behavioral pain models.
Product information
CAS Number: 1198117-23-5
Molecular Weight: 473.42
Formula: C24H19F4N3O3
Chemical Name: 7-fluoro-3-oxo-2-[2-(pyridin-2-yl)ethyl]-N-{[4-(trifluoromethoxy)phenyl]methyl}-2,3-dihydro-1H-isoindole-1-carboxamide
Smiles: O=C1C2=CC=CC(F)=C2C(C(=O)NCC2=CC=C(C=C2)OC(F)(F)F)N1CCC1=CC=CC=N1
InChiKey: GRXUKFHZQDPFAI-UHFFFAOYSA-N
InChi: InChI=1S/C24H19F4N3O3/c25-19-6-3-5-18-20(19)21(31(23(18)33)13-11-16-4-1-2-12-29-16)22(32)30-14-15-7-9-17(10-8-15)34-24(26,27)28/h1-10,12,21H,11,13-14H2,(H,30,32)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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