Retigabine dihydrochloride


Catalog No. Size PriceQuantity
M9949-2 Solid 2 mg $80
M9949-10 Solid 10 mg $240

Description

Ezogabine, also known as Retigabine, is an anticonvulsant used as an adjunctive treatment for partial epilepsies in treatment-experienced adult patients. The drug was developed by Valeant Pharmaceuticals and GlaxoSmithKline. Ezogabine works primarily as a potassium channel opener—that is, by activating a certain family of voltage-gated potassium channels in the brain. This mechanism of action is unique among antiepileptic drugs, and may hold promise for the treatment of other neurologic conditions, including migraine, tinnitus and neuropathic pain. (Source: http://en.wikipedia.org/wiki/Retigabine). Ezogabine is discontinued (DEA controlled substance).

Product information

CAS Number: 150812-13-8

Molecular Weight: 376.25

Formula: C16H20Cl2FN3O2

Chemical Name: ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate dihydrochloride

Smiles: Cl.Cl.CCOC(=O)NC1=CC=C(C=C1N)NCC1C=CC(F)=CC=1

InChiKey: WSGFOWNASITQHJ-UHFFFAOYSA-N

InChi: InChI=1S/C16H18FN3O2.2ClH/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11;;/h3-9,19H,2,10,18H2,1H3,(H,20,21);2*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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