Description
Y06036 (Compound 6i) is a potent and selective inhibitor of BET with antitumor activity. Y06036 binds to the BRD4(1) bromodomain with Kd of 82 nM.
Product information
CAS Number: 1832671-96-1
Molecular Weight: 427.27
Formula: C16H15BrN2O5S
Chemical Name: 5-Bromo-2-methoxy-N-(6-methoxy-3-methylbenzo[d]-isoxazol-5-yl)benzenesulfonamide
Smiles: CC1=NOC2=CC(OC)=C(C=C12)NS(=O)(=O)C1=CC(Br)=CC=C1OC
InChiKey: KVGNGFGTOSOVPB-UHFFFAOYSA-N
InChi: InChI=1S/C16H15BrN2O5S/c1-9-11-7-12(15(23-3)8-14(11)24-18-9)19-25(20,21)16-6-10(17)4-5-13(16)22-2/h4-8,19H,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO 85 mg/mL (198.94 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Maofeng Zhang, et al. J Med Chem. 2018 Apr 12;61(7):3037-3
Products are for research use only. Not for human use.
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