Description
PK9327 is a small-molecule stabilizer targeting cavity-creating p53 cancer mutations.
Product information
CAS Number: 2413987-20-7
Molecular Weight: 334.48
Formula: C21H22N2S
Smiles: CC1=CC=C(S1)C1=CC2=C(C=C1)C1=CC(CNC)=CC=C1N2CC
InChiKey: AYQRLKNUUZAQQN-UHFFFAOYSA-N
InChi: InChI=1S/C21H22N2S/c1-4-23-19-9-6-15(13-22-3)11-18(19)17-8-7-16(12-20(17)23)21-10-5-14(2)24-21/h5-12,22H,4,13H2,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Bauer MR, et al. Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. ACS Chem Biol. 2020 Mar 20;15(3):657-668.
Products are for research use only. Not for human use.
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