Description
Oteracil potassium is an antagonist of urate oxidase. It is used to induce hyperuricemia in mice.
Product information
CAS Number: 2207-75-2
Molecular Weight: 195.17
Formula: C4H2KN3O4
Synonym:
Potassium azaorotate
Potassium otastat
Potassium oxonate
Chemical Name: 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid potassium
Smiles: [K+].[O-]C(=O)C1N=C(O)N=C(O)N=1
InChiKey: IAPCTXZQXAVYNG-UHFFFAOYSA-M
InChi: InChI=1S/C4H3N3O4.K/c8-2(9)1-5-3(10)7-4(11)6-1;/h(H,8,9)(H2,5,6,7,10,11);/q;+1/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 9.09 mg/mL (46.57 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Shirasaka T, et al. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res. 1993 Sep 1;53(17):4004-9.
- Eraranta A, et al. Oxonic acid-induced hyperuricemia elevates plasma aldosterone in experimental renal insufficiency. J Hypertens. 2008 Aug;26(8):1661-8.
Products are for research use only. Not for human use.
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